from Philadelphia
Driving distance: 83.4 miles
Driving time: 1 hour, 31 minutes
Driving distance: 83.4 miles
Driving time: 1 hour, 31 minutes
| Mile | Instruction | For | Toward |
| 0.0 | Depart Philadelphia on S 12th St (South) | 43 yds | |
| 0.1 | Turn RIGHT (West) onto Walnut St | 0.2 mi | |
| 0.2 | Turn RIGHT (North) onto SR-611 [S Broad St] | 0.2 mi | |
| 0.4 | Turn RIGHT (East) onto S Penn Sq | 98 yds | |
| 0.4 | Turn LEFT (North) onto (S) Juniper St | 0.1 mi | |
| 0.6 | Turn LEFT (West) onto John F Kennedy Blvd | 0.1 mi | |
| 0.7 | Continue (West) on SR-3 [John F Kennedy Blvd] | 0.9 mi | |
| 1.6 | Turn off onto Ramp | 0.2 mi | I-76 / I-676 |
| 1.8 | Merge onto I-76 [Schuylkill Expy] (North) | 17.8 mi | |
| 19.7 | Turn off onto Ramp | 0.5 mi | I-76 / Harrisburg / Exits 23 - 1 |
| 20.2 | *Toll road* Merge onto I-76 [Pennsylvania Tpke] (West) | 39.5 mi | |
| 59.7 | At I-76 Exit 21, turn off onto Ramp | 0.5 mi | |
| 60.2 | Bear RIGHT (West) onto Spur Rd | 0.9 mi | |
| 61.1 | Turn LEFT (South) onto Ramp | 0.1 mi | |
| 61.2 | Continue (West) on US-222 | 15.1 mi | |
| 76.3 | At US-222 US-30 Exit, bear RIGHT (South) onto Ramp | 0.5 mi | |
| 76.7 | Continue (West) on US-30 [US-222] | 1.4 mi | |
| 78.1 | Bear RIGHT (West) onto Ramp | 0.3 mi | |
| 78.4 | Continue (South-West) on US-30 [Lincoln Hwy] | 3.8 mi | |
| 82.2 | At US-30 Centerville Rd Exit, bear RIGHT (West) onto Ramp | 0.3 mi | |
| 82.5 | Turn LEFT (South-East) onto Centerville Rd | 0.2 mi | |
| 82.7 | Turn RIGHT (West) onto Hempland Rd | 0.7 mi | |
| 83.4 | Arrive 3549 Hempland Rd, Lancaster, PA 17601 | ||
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